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However, a phase II study of the same combination in patients with NSCLC harboring activating EGFR mutations was terminated early due to inferiority in the linsitinib arm, together with increased toxicity that necessitated erlotinib dose reductions and discontinuations [189]
Because of the lack of stable 3D-structures, IDPs can sustain exposure to extremely harsh environmental conditions that would typically denature or unfold ordered proteins and render them dysfunctional (Uversky, 2017b)
10.1016/S0006-3495(02)73972-6 125 StefanoniD.ShinH
In bladder cancer cells, the poor permeability of Asp cells prevents the uptake of Asp by tumor cells from the environment
Modulation of gut microbiota and markers of metabolic syndrome in mice on cholesterol and fat enriched diet by butterfly pea flower kombucha
Villar-Martinez MD, Moreno-Ajona D, Goadsby PJ
