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Research consistently shows low toxicity, minimal immunogenicity, and no significant adverse effects in controlled experimental conditions, supporting its suitability for scientific investigation rather than therapeutic application

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DE cells were cultured in hepatoblast specification media at 37 C, 5% CO 2 for 6 days with media changes every 48 h (Siller et al., 2015

When used in low doses naltrexone (LDN) acts an immunomodulator