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Bar, J.A
Most people start noticing changes around the 23 month mark
All other molecules with sizes between these two extremes are partially included, as they can fit inside some but not all of the pores in the beads, and therefore possess an intermediate retention on the column and elute between the large (excluded) and small (totally included) molecules
Upon entering neurons, BHB can be converted to acetoacetate via -hydroxybutyrate dehydrogenase, which is then converted back to acetyl-CoA via -ketoacyl-CoA transferase, which subsequently enters the TCA cycle (Dhillon and Gupta, 2022)
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10.1016/j.tox.2007.10.029 Toxicology 14 den BraverM
