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This is also referred to as 'shotgun' proteomics, and most commonly used in the large-scale analysis of proteins and post-translational modifications

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In contrast, the L-chain lacks this ferroxidase site but features a higher density of acidic residues (e.g., glutamates and aspartates) on its inner surface, promoting iron nucleation and mineralization by facilitating the formation of the ferrihydrite core [7, 10]