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Description
We showed that HSV-1 enhanced the Keap1-dependent ubiquitination and degradation of Nrf2, which resulted in substantial reductions in the expression levels of antioxidative genes, thereby disturbing cellular redox homeostasis and promoting ferroptosis

doi:10.4088/JCP.19r12889 Daly EJ, Trivedi MH, Janik A, et al

10.3390/ijms140510497 [DOI] [PMC free article] [PubMed] [Google Scholar] 25.Colak E, Pap D
Part A 17 (23-24), 30453055

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Knezevic M., Gojkovic S., Krezic I., Zizek H., Malekinusic D., Vrdoljak B., Knezevic T., Vranes H., Drmic D., Staroveski M., et al

Its mechanism is direct lipolysis, making it a different tool with different patient profiles
