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F., Perez-Daz, J

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Current mechanistic studies mostly focus on isolated pathways (e.g., HIF-1, ARs signaling), ignoring the differential molecular effects and synergistic interactions of CIH and SF, as well as failing to establish a unified regulatory network centered on the tumor microenvironment (TME)

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125 This method also identified three main states of non-rectifying claudin-2 gating: open, stable, and transient closed states