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A study of rats exposed chronically to OTA, even at doses that resulted in 25% of the animals developing kidney tumor formation, the gene expression profile showed down-regulation of the antioxidant genes [73]

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doi: 10.3389/fpls.2018.00751 Received 15 February 2018 Accepted 16 May 2018 Published 07 June 2018 Volume 9 - 2018 Edited by Kendal Hirschi, Baylor College of Medicine, United States Reviewed by Toshiro Shigaki, The University of Tokyo, Japan