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PubMed: Ramaekers VT & Quadros EV

The use of glycyl-histidyl-lysine in culture systems

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Extended-interval dosing is associated with equivalent efficacy and reduced nephrotoxicity, with a non-significant trend toward lower ototoxicity in pooled analyses

Specifically, PRMT1 enhanced the protein function of UBE2m through arginine methylation at R169, and increased the neddylation level and protein stability of NEDD4, thereby inducing PPAR ubiquitination