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Activation of peripheral -opioid receptors by dermorphin [D-Arg2, Lys4] (14) amide leads to modality-preferred inhibition of neuropathic pain

doi: 10.1126/sciadv.abm2510 17 CorleyMJPangAPSDodyKMuddPAPattersonBKSeethamrajuHet al

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Vascular and angiogenic endpoints include: VEGF expression CD34 markers factor VIII markers vascular density endothelial response eNOS signalling NO pathway markers blood flow related tissue response This pathway helps explain why BPC-157 appears in so many different tissue models