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Wang, J., Arbuzova, A., Hangyas-Mihalyne, G

Quill TA, Wang D, Garbers DL

The competitive IRAP inhibitor 23 (HA08) enhances the numbers of dendritic spines in hippocampal cell cultures and HA08 treatment resulted in an increasing number of stubby and mushroom-like spines, a morphology typically associated with mature spines, which are believed to have strengthened synaptic connectivity

There is a significant body of research, mostly from the 2000s, on the homocysteine-lowering benefits of B12 in patients with end-stage renal disease and who are on haemodialysis (HD), 80100% of whom have elevated homocysteine levels

\Glucose Handling: Some evidence suggests improved glucose processing in patients with impaired glucose tolerance (Human Study)

Outcomes were analyzed using pooled relative risk (RR) and 95% confidence intervals (CI) for dichotomous outcomes and mean difference (MD) with 95% CI for continuous outcomes