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In the foundational mouse study, MOTS-c prevented diet-induced obesity and reversed insulin resistance without changes in food intake or exercise (Lee et al

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This finding highlights the complexity in choosing therapeutic targets, and the importance of studying the roles of DGAT1 and DGAT2, in steatosis and steatohepatitis

Theoretical methods We propose a methodology for the treatment of the data of the temperature dependence of the ZP method for determining lipid mixtures transition temperatures: first, a model function f (T, A) is used to predict the zeta potential of a DPPC-DMPC binary mixture of a given composition as a function of temperature (T) and an adjustment parameter (A)