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Animal-to-human amount translation is not straightforward and requires allometric scaling, and human pharmacokinetics, safety, and efficacy remain uncharacterized in published literature

10.1186/s13098-019-0484-0 107 PicardF.KurtevM.ChungN.Topark-NgarmA.SenawongT.Machado De OliveiraR.et al (2004)

PMCID: PMC7108996 Jimnez-Reina, L., Caete, R., de la Torre, M

1 This can impact one at any age but is more common in older age individuals being 60 years and older

Since the first-line intervention for obesity is typically lifestyle change(s) 4 , this study purposefully combined LD switch with 5A-1MQ treatment