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For example, reports of enzyme inhibition or modulation of signalling by silymarin derivatives in in vitro systems might partly reflect nonspecific adsorption or redox interference, rather than a real biochemical effect

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10.1186/s13045-022-01317-0 201 IppolitoL.ComitoG.ParriM.IozzoM.DuattiA.VirgilioF.et al (2022)

Cholongitas E, Papatheodoridis GV, Vangeli M, et al

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To address this, mixtures of several organic solvents were evaluated for the selective recrystallization of curcuminoids ( In a study by Ahmed et al