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Enzyme Inhibitors Co-administration of protease inhibitors can lower the enzymatic barrier and prevent degradation of proteins and peptides in the GI tract thereby facilitating intestinal absorption (Mahato et al., 2003
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Yes, this is known as seronegative autoimmune thyroiditis, or serum-negative Hashimotos

doi: 10.1006/cbir.1998.0253

Given the potency of this disinhibition of tonically active BNST afferents, other activators of the HPA axis, such as psychological stress, may also work by reducing BNST inhibitory tone onto PVH Crh neurons
