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Results: All seven patients were male, with an average age of onset of 39 12.87 years and an average disease duration of 5.00 3.92 years

We explored differentially expressed genes in our mutant strains within these pathways to determine if the observed phenotypic growth differences could be explained at this level of regulation

Such dysregulation has been linked to myriad pathologies, underscoring the clinical significance of maintaining ER redox homeostasis

Free radicals and non-radical derivatives of oxygen are collectively termed reactive oxygen species (ROS) [1]

[DOI] [PubMed] [Google Scholar] Zhang J., Zhang J., Li W., Chen R., Zhang Z., Zhang W., Tang Y., Chen X., Liu G., Lee C.S