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1 Introduction Periodontitis is a globally prevalent chronic inflammatory disease triggered by dysregulation of oral biofilm and host immune responses, serving as the primary cause of adult tooth loss ( A multi-platform analysis of human gingival crevicular fluid reveals that ferroptosis is an associated regulated cell death mechanism during the clinical progression of periodontitis ( Porphyromonas gingivalis can actively induce ferroptosis through multiple pathways ( This review systematically summarizes the molecular mechanisms of ferroptosis in periodontitis, with a focus on how dysregulated iron metabolism, reprogrammed lipid metabolism, and suppressed antioxidant defenses in the periodontal microenvironment regulate ferroptosis

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Enhance performance, speed up recovery

It also has potent antioxidant and anti-inflammatory effects, reducing oxidative stress in gingival tissue
Only an individual's specific needs and goals, as well as their healthcare provider's recommendations, can determine the exact MIC B12 dosage

It is a simple, widely applied technique (Singleton and Rossi 1965)