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Application of AP5 (an NMDA receptor antagonist) reduces these signals by 50%, and further addition of TFB-TBOA (to block EAAT responses) eliminates the transients completely

These compounds demonstrate antagonistic activity to the heat-sensitive transient receptor vanilloid 1 (TRPV1) in vitro and in vivo [27]

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Scientists often examine the peptide in laboratory models that look at endothelial cell behavior, fibroblast movement, and nitric-oxide related pathways