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Firstly, oxidative stress induces PKM2 translocation to the mitochondria where it phosphorylates Bcl2 at Thr69 site with the help of the chaperone protein HSP901

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Several clinical studies have been conducted on the use of NAC as a potential therapeutic agent for insulin resistance and type 2 diabetes [28] (Table 1)

(2022) indicates that S100A8 can mediate autophagy-dependent ferroptosis of microglia after SAH

investigated the dose-response risk of incident T2D as a function of GGT serum activity at baseline, assessed with the evaluation of 15,464 Japanese participants followed for up to 13 years [38]

Besides chronic infection, HBV can cause acute, fulminant and occult infection [258]
