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First in Human Clinical trials (FIH trials) play a critical role in bringing investigational new drugs or interventions to the clinical practice
Acad Radiol 29(5):736-747, 2022

Altered remodeling of nucleolar machineries in cultured hepatocytes treated with thioacetamide

Their skeleton comprises 2-phenyl--pyrone, which is involved in the heterocyclic pyrone ring connected with two phenyl rings [59]

As a specific example of a therapy contemplated by embodiments of the invention, the HGF mimics may be used for the treatment of dementia

It establishes a robust yet adaptable coordination with Cu(II) ions, utilizing the amino group of glycine, the imidazole nitrogen of histidine, and the -amino group of lysine
