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* Correspondence: Yunfeng Liu, [email protected]

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Ferroptosis-related proteins, Xc - anti-transport proteins, and neutral amino acid transporter proteins are available to provide T cells with the required Cys ( in vitro experiment has revealed that ferroptosis inhibitor FSP1 or GPX4 overexpression protects CD8 T cells from ferroptosis, while the utilization of GPX4 inhibitors significantly enhances the sensitivity of T cells to ferroptosis ( 4.5 Intestinal microorganisms in ferroptosis With the intensive investigation of the pathogenesis of RA, there is increasing evidence supporting the association between intestinal flora and RA