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Aberrant expression of G-6-P dehydrogenase may induce ferroptosis by disrupting NADPH and GSH metabolism

Nevertheless, given that iodoethane is a very good substrate also for the orthologue enzyme AgGSTE2-2 (data not shown) and this enzyme is the key enzyme responsible for DDT resistance in this species [4], there is no reason to believe that this assay will not work for Anopheles mosquitoes too