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That is, KDs have shown to be beneficial during a long duration ( 12 h), low-intensity ultra-endurance-type event, where mitochondrial beta-oxidation can match lower rates of ATP demand, whereas the combination of nutritional ketosis and high carbohydrate intake may confer performance benefits in endurance events of moderate intensity and durations of 8 h (54)

Of note, the aforementioned studies were performed in different models, including species (mouse vs

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Pre-publication history The pre-publication history for this paper can be accessed here: Additional information Competing interests The authors declare that they have no competing interests

Neurology 61, 17891791

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