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doi: 10.2174/156720508783954758

doi: 10.1080/09553002.2019.1589653

This study was supported by the Scientific Research Project Unit of Suleyman Demirel University (project code: TSG-2023-9010)

S., Pasquali, M

The results showed that a genetic variant in the GRIK2 gene was more common in people with ME/CFS, and that the gene expression for that gene was decreased by 10-fold in patients compared to controls.[ref] Related article: Glutamate receptor gene variants Circadian clock gene, NPAS2: The study mentioned above also identified a circadian clock gene variant as differentially expressed (10-fold difference) and a variant in the gene as increasing susceptibility to ME/CFS.[ref] Rare mutations: A 2025 Stanford study using the HEAL2 deep learning framework analyzed whole genome sequences from 1,075 ME/CFS patients

[DOI] [PubMed] [Google Scholar] 33.Dragan G.I., Wagner W., Ploesteanu E