glutathione systematic name Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Solved 1. Draw the structure
Description
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GSH scavenges free radicals and reactive oxygen species (ROS), protecting cells from damage caused by oxidative stress
in contrast, the cytotoxicity of the PtII drugs, cisplatin and carboplatin, was only significantly increased in one of the two relatively resistant lines (SKOV-3) and in the sensitive (CH1) line after GSH depletion
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