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When these peptides bind to GHS-R, they initiate intracellular signaling, that leads to the release of growth hormone from pituitary somatotroph cells

On Matrigel, cells were dissociated using TrypLE Express Enzyme (Thermo Fisher Scientific, 12605010) 2 min/37 C, dissociated in fresh media, centrifuged at 200 g for 4 min at 4 C, and resuspended in fresh media

[DOI] [PubMed] [Google Scholar] 91.Kemp S.F

GH-IGF1 axis dysregulation enhances the synergistic effect of the promotion of uncontrolled cell proliferation, cell migration and invasion, thus promoting cancer initiation and metastasis (Dehkhoda et al., 2018)

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Figure 3 Manganese (II) compounds are promising candidates for clinical use as MRI contrast agents owing to their relatively high electronic spin and fast water exchange rate