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Because of the above caveats, modern pharmacology research has refocused on natural products, mainly of plant origin, although bacteria, fungi, and animal sources cannot be ignored

This process, referred to as NOS uncoupling, describes a transition in the activity of several NOS isoforms, including constitutive eNOS, nNOS, and iNOS

[DOI] [PMC free article] [PubMed] [Google Scholar] 280.Johnsen K.B., Bak M., Kempen P.J., Melander F., Burkhart A., Thomsen M.S., Nielsen M.S., Moos T., Andresen T.L

Functional approaches typically prioritize diet, gut health, and other supportive therapies first, using chelation only in carefully monitored situations

Treatment of chronic hepatitis C virus infection via antioxidants: Results of a phase I clinical trial

Recently, a novel thieno[3,2-c]pyridine compound called JFY-001, designed to target copper ions specifically, demonstrated significant potential in inhibiting colorectal cancer cell proliferation, inducing cuproptosis, and disrupting cellular metabolic processes [99]