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When neutrophils and macrophages get stimulated by a phagocytic stimulus, produces a respiratory burst, which is characterized by an increase in oxygen consumption, activation of the Hexose-Monophosphate (HMP) shunt and generation of Free Radicals (FR), Reactive Oxygen Species (ROS) and their metabolic products

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In recent years, mounting evidence has demonstrated the therapeutic potential of bioactive compounds for DKD, attracting widespread public attention

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