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Additionally, a recent study by Nhu and colleagues further highlighted the role of gut-brain axis disruption, possibly tied to BA metabolism, in psychological symptoms associated with FM, rather than pain 40

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This sequestration increases the pool of free G-actin available for cytoskeletal remodeling, enabling cells to reorganize their internal architecture and migrate toward injury sites

The results showed that the developed cardiac constructs achieved rapid coordinated cardiac contraction (mean displacement of approximately 13.4 m at day 5, and 14.7 m at day 30), progressive sarcomere maturation (sarcomere length 0.95 at day 1 compared to 1.99 at day 30), and increased expression of cardiomyocyte maturation genes such as MYL2, MYH7, and TNNI3

The tubes were stored in the refrigerator for 7 days in the dark to allow sufficient time for pigment diffusion