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As expected, LPS caused a substantial increase in the fold change expression of IL-1 in comparison to the vehicle treated cells (Veh: 1.31 0.52, LPS: 570.8 95.17)

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For example a 500 microgram (mcg.) dose can be administered in a single spray of 0.65 mg (which because it is approximately equal to 0.65 ml is better thought of in milliliters) in the preferred embodiment of the invention