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This study shows that glutamate can be converted to -ketoglutarate in cancer cells by either GLUD or aminotransferases, and that the relative contribution of each pathway varies by cell type

FoxOs transcriptionally induce E3 ligases like Atrogin-1/MAFbx and MuRF1, as well as autophagy genes including BNIP3, LC3, and Atg12