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Most of the risks recorded in scientific studies are associated with incorrect dosage and risks of intravenous administration by untrained individuals

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Instead, very high serum levels often suggest impaired metabolism or an underlying medical condition

Furthermore, the threshold effect is consistent with the concept that methionine synthase activity may become saturated beyond a certain B12 concentration [17], explaining the diminishing returns observed at higher levels

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Exercise can reduce A levels and enhance mitochondrial function, thereby improving learning and memory ability (Li et al., 2019)