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How TUDCA Works Tauroursodeoxycholic acid is a hydrophilic bile acid formed when ursodeoxycholic acid is conjugated with the amino acid taurine

doi: 10.1016/j.lfs.2021.119942 12 BarnesRPFouquerelEOpreskoPL

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We observed a consistent increase in sensitivity, or reduced IC 50 value, for mutant cells treated with doxycycline but not parental OVCAR5 cells, indicating that induction of mutant p53 sensitized cells to APR-246 (Fig

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