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However, the relevance of these findings and hence of the role of lysosomal cathepsin D in in vivo APAP-mediated acute liver failure is uncertain given the minor role of CYP3A4 in APAP metabolism (see above)
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This also links neuroinflammation to oxidative stress in epilepsy (198)
1a and 5a)
It's a central mechanism of injury, whether the initial cause is diabetes, high blood pressure, or exposure to toxins
