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Description
Sporadic inclusion-body myositis: conformational multifactorial ageing-related degenerative muscle disease associated with proteasomal and lysosomal inhibition, endoplasmic reticulum stress, and accumulation of amyloid-42 oligomers and phosphorylated tau
In addition to the cutaneous and subcutaneous MCT forms, a visceral form is also considered, characterized by infiltration into the abdominal lymph nodes, liver, and spleen [15], and disseminated mastocytosis, when there is systemic involvement in the bone marrow [52]
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