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Hyperpolarization resulting from this mechanism will result in deactivation of voltage-dependent Ca channels, resulting in decreased Ca influx, which will favor smooth muscle relaxation

10.1038/s41598-023-38134-5 3 AlshabiA

Padayatty et al., 2004 Glutathione earns its third-place ranking through a combination of mechanistic breadth, strong clinical evidence, and particular relevance to the Indian environmental context

10.1158/0008-5472.CAN-19-3670 228 SmithA

Specifically, MNPs exposure causes oxidative stress, induce apoptosis upregulating Bad and reducing Bcl-2 levels, endoplasmic reticulum stress, autophagy, activation of MAPK and mammalian target of rapamycin (mTOR) signaling and increased extracellular vesicles release [99,100]

Naringenin supplementation for 1 month can reduce lipid peroxidation and decrease the expression of PKC, NF-B, cyclin D1(CCND1) and cyclin-dependent kinase 4 (CDK4), thereby inhibiting the proliferation of glioma cells in mouse models (366)