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Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

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Studies utilizing GPX4 degradation to induce ferroptosis revealed that lipid peroxidation propagates ferroptotic signaling through intercellular transfer via plasma membrane contact, amplifying necrotic tissue expansion 31

135 demonstrated that induction of oxidative stress through the small molecule lanperisone kills mouse embryonic fibroblasts transfected with mutant KRAS and restrains their growth in vivo