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The researchers discovered that both patient cohorts exhibited significant signs of elevated oxidative stress and consequent mitochondrial damage

doi: 10.3389/fimmu.2019.00009

Y-BP: Conceptualization, Data curation, Methodology, Project administration, Validation, Writingoriginal draft, Writingreview and editing
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These signals trigger the transformation of fibroblasts into CAFs, which secrete a range of matrix proteins, such as collagen and fibronectin