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Further investigation is needed to reveal whether skin microbes contribute to this process via altered community composition and dysregulated interactions with surrounding epidermal cells (Fig

GSH is known to modulate DNA synthesis by maintaining reduced glutaredoxin or thioredoxin, which are required for the activity of ribonucleotide reductase, the rate-limiting enzyme in DNA synthesis (Holmgren, 1981)

doi: 10.3389/fchem.2020.598722

Metals are often found to be stored in the vacuole, which is believed to be the primary source of metal requisitioning in root cells (Shabbir et al., 2020)

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Although we felt the homogenization method may be acceptable for labs with the facilities to make the particles and that these experiments allowed us to optimize the parameters necessary for protein purification, we felt that further improvements were possible