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3.2 Destruction of periodontal soft tissues The integrity and function of PDLFs, essential for softtissue homeostasis, are compromised by ferroptosis through a twofold assault on collagen: synthesis is reduced because PDLF viability and activity are impaired, while degradation is accelerated by ferroptosisassociated ROS and proinflammatory mediators ( in vitro primary cell models, indicate that ferroptosis in periodontal ligament fibroblasts serves as an active driver of soft tissue destruction

The baseline of the detector should remain stable

Comparisons were performed with pair-wise PERMANOVA in Fig

Abbreviations TRY: Triptychon CPC: Caprice GFP: Green fluorescent protein GL1: Glabra1 GL3: Glabra3 TTG1: Transparent testa glabra1 YFP: Yellow fluorescent protein GUS: Glucoronidase ETC3: Enhancer of triptychon and caprice3 TCL1: Trichomless1 SPL: Squamosa promoter binding protein like (SPL) References Hulskamp M: Plant Trichomes: A Model for Cell Differentiation

C.SchmalhoferO.ZhuF.SonntagA.et al (2009)