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Understanding and Managing Withdrawal Syndromes after Discontinuation of Antidepressant Drugs
10.7326/M16-0271 65 KhanS.WaliullahS.GodfreyV.KhanM
doi: 10.1038/nri2448 75 MurrayPJWynnTA
NNMT (Nicotinamide N-methyltransferase) is an enzyme that adds a methyl group to nicotinamide (a form of vitamin B3)
Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury
The Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus-Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 trial assessed the impact of saxagliptin on cardiovascular outcomes and reported an increase in rates of hospitalisation for HF with no impact on ischaemic events.85 Further clinical trials have been conducted, reporting no increased risk of HF or other cardiac outcomes,86 however, these trials still report no improvement
