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Clin Exp Gastroenterol 15:105120 Ajoolabady A, Kaplowitz N, Lebeaupin C, Kroemer G, Kaufman RJ, Malhi H, Ren J (2023) Endoplasmic reticulum stress in liver diseases

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[22] In studies of human recombinant MTHFR, the protein encoded by 677T loses its FAD cofactor three times faster than the wild-type protein

This counteraction involves, in particular, a prolonged QTc interval [30,59], a thing correlated with pulmonary pressures and right-ventricular dilation, and inversely correlated with RV function [62]

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