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Description
cGAS) consisting of an N-terminal, and inactive catalytic domain is activated by binding to cytosolic viral DNA and mitochondrial DNA from damaged mitochondria 40

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This included a reduction in mRNA levels of Grin2b , Nrxn1 , Cacna1e , and Gabrb2 , as well as the dysregulation of other key genes, such as Reelin , Mecp2 , Tbr1 , and Kenmal

Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study
