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ROS also play roles in drug resistance via activation of NF-B, which triggers pro-inflammatory cytokine secretion

It also has wound healing and anti-cancerous activities (melanoma) [336]
Therefore, in order to prevent and treat the disease and improve prognosis, there is an urgent need to explore the pathogenesis of CCVDs, as well as new therapeutic strategies

10.1016/j.brainres.2015.03.018 88 RossiR.Dalle-DonneI.MilzaniA.GiustariniD
