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Taylor R, Al-Mrabeh A, Zhyzhneuskaya S, Peters C, Barnes AC, Aribisala BS, et al

the difference lies in distribution pathway and regulatory classification, not medication safety or effectiveness

At 72 weeks, tirzepatide produced a mean weight reduction of 20.2% compared to 13.7% for semaglutide

Suddenly they seem, (with some notable provisos see below), like a real possibility

However, caution is warranted - GLP-1 agonists can also cause periodic loose stools or gastric upset (e.g

This article explains the evidence around stopping GLP-1 therapy, what to expect when treatment ends, and how to discontinue safely under medical supervision in line with UK clinical guidance
