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Please consult a medical professional to determine whether or not GLP-1 medications could be appropriate for you

The mechanism is the ubiquitin-proteasome pathway

With glaucoma pharmacotherapy reducing intraocular pressure, there is a common concern given to the potential impact of these drugs on the corneal endothelium [74,75]

BIBER, T.U.L., MYLLE, M., BAINES, A.D., & GOTTSCHALK, C.W

Raj GM, Raveendran R (2019) Introduction to basics of pharmacology and toxicology: volume 1: general and molecular pharmacology: Principles of drug action

Zhao et al., 2025) that MSCs can not only directly differentiate into nucleus pulposus-like cells, replenishing the missing cell population (Li et al., 2025), but also play a key role through paracrine actions: on one hand, by secreting growth factors (such as TGF-, IGF-1) to activate anabolic pathways and promote ECM synthesis (Tang et al., 2025)