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Xu Y, Sun J, Sheard MA, Tran HC, Wan Z, Liu WY

Similar content being viewed by others Introduction Vitamin B12 (B12), historically known as the anti-pernicious anemia factor by its ability to cure pernicious anemia, was first documented in 1926 1

White arrows indicate nuclear-to-cytoplasmic translocation of HMGB1/2


doi: 10.1053/j.gastro.2024.05.014

For adaptive immunity, it restores the balance of T-cell subsets, promoting regulatory Treg differentiation, inhibiting pathogenic Th17 and autoreactive CD8 + T cell activation, and regulating Tfh cell function
