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This hormone normally binds to a receptor on skin cells called melanocortin-1 receptor (MC1R)

This led to the identification of microbiota-derived bile acids (host-microbiota, Box 1) that can modulate anti-tumour immunity through antagonising the transcription factor androgen receptor (AR) in CD8 T cells 49

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The enzymes affected belong to one of three categories: Very long-chain acyl-CoA dehydrogenase (VLCAD): The symptoms that result from deficiencies in VLCAD were originally ascribed to loss of long-chain acyl-CoA dehydrogenase (LCAD) activity

[DOI] [PubMed] [Google Scholar] Abdelhamid H

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