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Besides their proven role in cell and tissue injury, oxidants participate in essential physiological functions, including host defense and neovascularization (Babior, 1999

MYH (MUTYH) is a human mismatch-specific adenine-DNA glycosylase homologous to the E

Edaravone showed potent antioxidant and radical scavenging activities in various pathologies, such as cerebral ischemia, stroke and amyotrophic lateral sclerosis [202,203,204], also improving oxidative stress-induced mitochondrial impairment in various diseases [205,206]