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Martinez FJ, de Andrade JA, Anstrom KJ, et al

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Aging remains the most prominent risk factor, amplifying neuronal susceptibility due to diminished proteostasis, mitochondrial function, and bloodbrain barrier integrity [28]

Pyroptosis in NAFLD Previous studies have provided evidence supporting the involvement of pyroptosis, induced by the activation of inflammasomes, in the pathogenic mechanism of NAFLD