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A mediation analysis revealed that while a change in body weight was the primary contributing factor (72%) to the reduction in SBP, other factors, including estimated glomerular filtration rate and HbA 1c , were also involved to a lesser degree
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It prevented and reversed hepatocyte enlargement, fatty liver changes, and liver weight increases
Early prediction and impact assessment of CYP3A4-Related Drug-Drug interactions for Small-Molecule anticancer drugs using Human-CYP3A4-Transgenic mouse models
